Neuron shape digital reconstruction method and system

The invention discloses a neuron shape digital reconstruction method and a neuron shape digital reconstruction system, and aims at morphological data of neuron whole brain distribution, especially data lacking path node radius information, in combination with a submicron resolution image data set ob...

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Hauptverfasser: JIANG SIQI, GONG HUI, PAN ZHENGYU, LI AN'AN, LUO QINGMING, WAN MENGYU
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a neuron shape digital reconstruction method and a neuron shape digital reconstruction system, and aims at morphological data of neuron whole brain distribution, especially data lacking path node radius information, in combination with a submicron resolution image data set obtained by a fiber optical imaging technology. And the method for optimizing the protrusion path and automatically estimating the path node radius, which can be used for neuron shape reconstruction, is designed. According to the method, the neuron protrusion path of the existing neuron protrusion can be corrected, the fitting degree of the neuron protrusion path and the center line of the neuron protrusion in the image is improved, and the phenomenon of neuron protrusion path sawtooth can be eliminated. Meanwhile, the radius of each neurite path node is automatically estimated in combination with the neuron image and the optimized neurite path, and the accuracy and calculation efficiency of the radius of the existin