Micro-fluidic chip for simulating biological mechanical force of tubular organ of human body
The invention provides a micro-fluidic chip for biological mechanical force simulation of a tubular organ of a human body, the chip comprises a double-layer channel which is coaxial inside and outside, the inner surface of the inner-layer channel of the double-layer channel is used for adhering cell...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention provides a micro-fluidic chip for biological mechanical force simulation of a tubular organ of a human body, the chip comprises a double-layer channel which is coaxial inside and outside, the inner surface of the inner-layer channel of the double-layer channel is used for adhering cells to simulate the tubular organ, the inner-layer channel is a circular channel, and the outer surface of the inner-layer channel is used for adhering cells to simulate the tubular organ. A diaphragm is arranged between the inner-layer channel and the outer-layer channel of the double-layer channel, and the diaphragm drives the inner-layer channel to stretch or extrude under the condition that the diaphragm is stressed so as to simulate the dilatation or contraction of the tubular organ. According to the chip, circular channel culture cells are used for simulating tubular organs such as blood vessels, intestinal tracts and tracheas, the structure is closer to a physiological tissue structure, deformation occurs in a |
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