Preparation method of notopterygium root formula granules
The invention discloses a preparation method of notopterygium root formula granules. The preparation method comprises the following steps: (1) extracting volatile oil; (2) water extraction; (3) vacuum concentration; (4) clathration of volatile oil; (5) spray drying; (6) sieving and mixing; and (7) d...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention discloses a preparation method of notopterygium root formula granules. The preparation method comprises the following steps: (1) extracting volatile oil; (2) water extraction; (3) vacuum concentration; (4) clathration of volatile oil; (5) spray drying; (6) sieving and mixing; and (7) dry granulation. According to the invention, the problem that heat-sensitive components such as ferulic acid, notopterygium alcohol, isoimperatorin and other organic acid and coumarin chemical components in notopterygium are easy to degrade and lose is solved, and the product quality of the notopterygium formula granules is improved; the problems of high temperature and long heating time of intermediates such as extracting solution and concentrated solution in the traditional Chinese medicine production process are solved, and the method is suitable for industrial mass production.
本发明公开了一种羌活配方颗粒的制备方法,包括如下步骤:(1)挥发油提取;(2)水提取;(3)减压浓缩;(4)挥发油包合;(5)喷雾干燥;(6)过筛混合;(7)干法制粒。本发明解决了羌活中热敏性成分如阿魏酸、羌活醇、异欧前胡素等有机酸类、香豆素类化学成分易降解损失的问题,提高 |
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