Method for establishing mouse or rat male and female hormone imbalance type prostatic hyperplasia model

The invention discloses a method for establishing a mouse or rat male and female hormone imbalance type prostatic hyperplasia model, and belongs to the technical field of medical evaluation and detection. The method comprises the following steps: 1, feeding mice or rats; 2, preparing male and female hormone sustained-release granules; 3, establishing a mouse or rat male and female hormone imbalance type prostatic hyperplasia model; and 4, evaluating the influence of the male and female hormone sustained-release granules on the prostate of the mouse (rat). Androgen and estrogen are combined to promote prostate growth of male mice or rats by utilizing the male and female hormone sustained-release agent. According to the model, estrogen induction is added on the basis of androgen, the model is closer to the hormone internal environment of a benign prostatic hyperplasia patient, sustained-release particles are adopted, medicine injection is not needed every day, toxic and side effects caused by the fact that the