Nucleotide probes

Compounds useful as nucleic acid probes are disclosed. In certain embodiments, the compounds have the following structure (I): or a stereoisomer, tautomer or salt thereof, where M, L1a, L2, L8, L1b, L3, L5, L6, L7, L4, R1, R2, R3, R4, R5, Ra, Rb, Rc, Rd, m, n, q, and w are as defined herein. Methods...

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Hauptverfasser: DOMINGUEZ MARK, MATRAY TRACY, KUANG ERIC
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creator DOMINGUEZ MARK
MATRAY TRACY
KUANG ERIC
description Compounds useful as nucleic acid probes are disclosed. In certain embodiments, the compounds have the following structure (I): or a stereoisomer, tautomer or salt thereof, where M, L1a, L2, L8, L1b, L3, L5, L6, L7, L4, R1, R2, R3, R4, R5, Ra, Rb, Rc, Rd, m, n, q, and w are as defined herein. Methods related to the preparation and use of such compounds are also provided. 公开了可用作核酸探针的化合物。在某些实施方案中,所述化合物具有以下结构(I):或其立体异构体、互变异构体或盐,其中M、L1a、L2、L8、L1b、L3、L5、L6、L7、L4、R1、R2、R3、R4、R5、Ra、Rb、Rc、Rd、m、n、q和w如本文中定义。还提供了与这样的化合物的制备和用途有关的方法。
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In certain embodiments, the compounds have the following structure (I): or a stereoisomer, tautomer or salt thereof, where M, L1a, L2, L8, L1b, L3, L5, L6, L7, L4, R1, R2, R3, R4, R5, Ra, Rb, Rc, Rd, m, n, q, and w are as defined herein. Methods related to the preparation and use of such compounds are also provided. 公开了可用作核酸探针的化合物。在某些实施方案中,所述化合物具有以下结构(I):或其立体异构体、互变异构体或盐,其中M、L1a、L2、L8、L1b、L3、L5、L6、L7、L4、R1、R2、R3、R4、R5、Ra、Rb、Rc、Rd、m、n、q和w如本文中定义。还提供了与这样的化合物的制备和用途有关的方法。</description><language>chi ; eng</language><subject>ADHESIVES ; BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS OR TEST PAPERS THEREFOR ; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ; DERIVATIVES THEREOF ; DYES ; ENZYMOLOGY ; MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FORELSEWHERE ; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS ; METALLURGY ; MICROBIOLOGY ; MISCELLANEOUS APPLICATIONS OF MATERIALS ; MISCELLANEOUS COMPOSITIONS ; MUTATION OR GENETIC ENGINEERING ; NATURAL RESINS ; NUCLEIC ACIDS ; NUCLEOSIDES ; NUCLEOTIDES ; ORGANIC CHEMISTRY ; PAINTS ; POLISHES ; PROCESSES OF PREPARING SUCH COMPOSITIONS ; SPIRITS ; SUGARS ; VINEGAR ; WINE</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20220830&amp;DB=EPODOC&amp;CC=CN&amp;NR=114981451A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20220830&amp;DB=EPODOC&amp;CC=CN&amp;NR=114981451A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>DOMINGUEZ MARK</creatorcontrib><creatorcontrib>MATRAY TRACY</creatorcontrib><creatorcontrib>KUANG ERIC</creatorcontrib><title>Nucleotide probes</title><description>Compounds useful as nucleic acid probes are disclosed. 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Methods related to the preparation and use of such compounds are also provided. 公开了可用作核酸探针的化合物。在某些实施方案中,所述化合物具有以下结构(I):或其立体异构体、互变异构体或盐,其中M、L1a、L2、L8、L1b、L3、L5、L6、L7、L4、R1、R2、R3、R4、R5、Ra、Rb、Rc、Rd、m、n、q和w如本文中定义。还提供了与这样的化合物的制备和用途有关的方法。</description><subject>ADHESIVES</subject><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS OR TEST PAPERS THEREFOR</subject><subject>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</subject><subject>DERIVATIVES THEREOF</subject><subject>DYES</subject><subject>ENZYMOLOGY</subject><subject>MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FORELSEWHERE</subject><subject>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MISCELLANEOUS APPLICATIONS OF MATERIALS</subject><subject>MISCELLANEOUS COMPOSITIONS</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>NATURAL RESINS</subject><subject>NUCLEIC ACIDS</subject><subject>NUCLEOSIDES</subject><subject>NUCLEOTIDES</subject><subject>ORGANIC CHEMISTRY</subject><subject>PAINTS</subject><subject>POLISHES</subject><subject>PROCESSES OF PREPARING SUCH COMPOSITIONS</subject><subject>SPIRITS</subject><subject>SUGARS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZBD0K03OSc0vyUxJVSgoyk9KLeZhYE1LzClO5YXS3AyKbq4hzh66qQX58anFBYnJqXmpJfHOfoaGJpYWhiamho7GxKgBANn5H7M</recordid><startdate>20220830</startdate><enddate>20220830</enddate><creator>DOMINGUEZ MARK</creator><creator>MATRAY TRACY</creator><creator>KUANG ERIC</creator><scope>EVB</scope></search><sort><creationdate>20220830</creationdate><title>Nucleotide probes</title><author>DOMINGUEZ MARK ; MATRAY TRACY ; KUANG ERIC</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN114981451A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2022</creationdate><topic>ADHESIVES</topic><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS OR TEST PAPERS THEREFOR</topic><topic>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</topic><topic>DERIVATIVES THEREOF</topic><topic>DYES</topic><topic>ENZYMOLOGY</topic><topic>MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FORELSEWHERE</topic><topic>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MISCELLANEOUS APPLICATIONS OF MATERIALS</topic><topic>MISCELLANEOUS COMPOSITIONS</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>NATURAL RESINS</topic><topic>NUCLEIC ACIDS</topic><topic>NUCLEOSIDES</topic><topic>NUCLEOTIDES</topic><topic>ORGANIC CHEMISTRY</topic><topic>PAINTS</topic><topic>POLISHES</topic><topic>PROCESSES OF PREPARING SUCH COMPOSITIONS</topic><topic>SPIRITS</topic><topic>SUGARS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>DOMINGUEZ MARK</creatorcontrib><creatorcontrib>MATRAY TRACY</creatorcontrib><creatorcontrib>KUANG ERIC</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>DOMINGUEZ MARK</au><au>MATRAY TRACY</au><au>KUANG ERIC</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Nucleotide probes</title><date>2022-08-30</date><risdate>2022</risdate><abstract>Compounds useful as nucleic acid probes are disclosed. In certain embodiments, the compounds have the following structure (I): or a stereoisomer, tautomer or salt thereof, where M, L1a, L2, L8, L1b, L3, L5, L6, L7, L4, R1, R2, R3, R4, R5, Ra, Rb, Rc, Rd, m, n, q, and w are as defined herein. Methods related to the preparation and use of such compounds are also provided. 公开了可用作核酸探针的化合物。在某些实施方案中,所述化合物具有以下结构(I):或其立体异构体、互变异构体或盐,其中M、L1a、L2、L8、L1b、L3、L5、L6、L7、L4、R1、R2、R3、R4、R5、Ra、Rb、Rc、Rd、m、n、q和w如本文中定义。还提供了与这样的化合物的制备和用途有关的方法。</abstract><oa>free_for_read</oa></addata></record>
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subjects ADHESIVES
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
DERIVATIVES THEREOF
DYES
ENZYMOLOGY
MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FORELSEWHERE
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MISCELLANEOUS APPLICATIONS OF MATERIALS
MISCELLANEOUS COMPOSITIONS
MUTATION OR GENETIC ENGINEERING
NATURAL RESINS
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PAINTS
POLISHES
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
SUGARS
VINEGAR
WINE
title Nucleotide probes
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