Bioabsorbable nerve scaffold and preparation method thereof

The invention provides a bioabsorbable nerve scaffold and a preparation method thereof, and hydrophilic block molecules, hydrophobic block molecules, a prepolymer containing an isocyanate functional group and a magnetic nano material are used as raw materials and are blended and processed into a hol...

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1. Verfasser: LAN ZHIYUAN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention provides a bioabsorbable nerve scaffold and a preparation method thereof, and hydrophilic block molecules, hydrophobic block molecules, a prepolymer containing an isocyanate functional group and a magnetic nano material are used as raw materials and are blended and processed into a hollow tubular structure. The nerve scaffold can be gradually degraded in human tissues, and has good mechanical properties and a good nerve repairing effect. Wherein the hydrophilic block molecule is polyester polyol or polyether polyol, the hydrophobic block molecule is obtained by carrying out hydroxyl end group encapsulation on polylactic acid, polyglycolide or polycaprolactone, and the prepolymer is obtained by carrying out a reaction on the hydrophilic block molecule, the hydrophobic block molecule and isocyanate. The main body structure of the hydrogel is obtained through polymerization reaction of hydrophilic block molecules, hydrophobic block molecules and isocyanate, and the hydrogel has good mechanical prop