Total synthesis method of natural product aurantioclavine racemate

The invention relates to the technical field of organic synthesis, in particular to a total synthesis method of a natural product aurantioclavine racemate. The preparation method comprises the following steps: taking 4-bromoindole-3-formaldehyde as an initial raw material, carrying out nucleophilic addition reaction with nitromethane and ammonium acetate, and carrying out post-treatment to obtain a first compound; carrying out reduction reaction on the first compound and lithium aluminum hydride to obtain a second compound; carrying out protection reaction on the second compound and paratoluensulfonyl chloride to obtain a third compound; carrying out Heck reaction on the third compound, 2-methyl-3-butene-2-alcohol, a metal catalyst and a ligand to obtain a fourth compound; carrying out cyclization reaction on the fourth compound and lewis acid to obtain a fifth compound; finally, the fifth compound, sodium and naphthalene are subjected to a deprotection reaction, and the final natural product aurantioclavine