Compound, preparation method thereof, pharmaceutical composition and application of compound in preparation of EED inhibitor

The invention relates to the technical field of medicines, and provides a compound, a preparation method thereof, a pharmaceutical composition and application of the compound in preparation of an EED inhibitor. The compound provided by the invention can achieve the purpose of treating or preventing tumors by inhibiting the activity of EED, and a therapeutically effective amount of one or more of the compounds, stereoisomers, pharmaceutically acceptable salts, hydrates, solvates or isotope compounds thereof can be administered to patients needing the treatment or prevention. Therefore, the purpose of treatment or prevention is achieved. The result of the embodiment shows that the compound provided by the invention has a relatively good effect of inhibiting the activity of EED. 本发明涉及药物技术领域，提供了一种化合物及其制备方法以及药物组合物和在制备EED抑制剂中的应用。本发明提供的化合物能够通过抑制EED活性达到治疗或预防肿瘤目的，可以通过向需要此种治疗或预防的患者给予治疗有效量的一种或多种本发明化合物、其立体异构、药学上可接受的盐、水合物、溶剂合物或同位素化合物，以达到治疗或预防的目的。实施例结果表明，本发明提供的化合物具有较好的抑制EED活性的作用。