Biscarbonyl ligand as well as preparation method and application thereof

Biscarbonyl ligand as well as preparation method and application thereof

The invention relates to the technical field of medical compounds, in particular to a dicarbonyl ligand as well as a preparation method and application thereof.The dicarbonyl ligand has very high growth inhibition capacity on human malignant melanoma cells (A375 cancer cells) and is beneficial to de...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: LIU ZHUANGFENG, HUANG HUAIYI, XIE YUZHEN, WEI SIQI, FAN ZHONGXIAN, ZHU ZILIN, WEI LI, LIN YICAO
Format: Patent
Sprache:chi ; eng
Schlagworte:
ADHESIVES
CHEMISTRY
DYES
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FORELSEWHERE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MISCELLANEOUS APPLICATIONS OF MATERIALS
MISCELLANEOUS COMPOSITIONS
NATURAL RESINS
ORGANIC CHEMISTRY
PAINTS
POLISHES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The invention relates to the technical field of medical compounds, in particular to a dicarbonyl ligand as well as a preparation method and application thereof.The dicarbonyl ligand has very high growth inhibition capacity on human malignant melanoma cells (A375 cancer cells) and is beneficial to development of efficient anti-cancer drugs, and the IC50 value of a tpy-dCO ligand is as low as 3.23 mu mol.L . 本发明涉及医用化合物技术领域，具体涉及一种双羰基配体及其制备方法和应用，本发明的双羰基配体对人恶性黑色素瘤细胞(A375癌细胞)具有很强的生长抑制能力，有助于开发高效的抗癌药物，其中，tpy-dCO配体的IC50值低至3.23μmol·L-1。