Application of procyanidine in resisting novel coronavirus

The invention provides application of procyanidine in resisting novel coronavirus, and particularly relates to application of procyanidine in preparing drugs, disinfection articles or protective articles for resisting novel coronavirus. According to the application disclosed by the invention, experiments prove that the procyanidine can be used for strongly inhibiting the channel current mediated by SARS-CoV-2-E; the procyanidine can be used for specifically protecting the cells from cell death mediated by the SARS-CoV-2-E channel; in cells infected by the virus, the procyanidine can inhibit the replication of the SARS-CoV-2 virus and obviously reduce the virus titer. 本发明提供了原花青素在抗新型冠状病毒中的应用，具体涉及原花青素在制备抗新型冠状病毒的药物、消毒用品或防护用品中的应用。本发明通过实验证实了，原花青素能够强效地抑制SARS-CoV-2-E介导的通道电流；原花青素能够特异性地保护细胞免于由SARS-CoV-2-E通道介导的细胞死亡；在病毒侵染的细胞中，原花青素能够抑制SARS-CoV-2病毒的复制，显著降低病毒滴度。