Pyrrolidine derivative, and pharmaceutical composition for preventing or treating beta-amyloid or tau protein-related diseases comprising same
Provided are: a novel pyrrolidine derivative or a pharmaceutically acceptable salt thereof; and a novel pyrrolidine derivative containing the same, which has an effect of inhibiting the aggregation of beta-amyloid protein and/or Tau protein and/or an effect of degrading aggregates of beta-amyloid pr...
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| creator | KIM DA-YONG KIM SUNG-HWAN LEE WON-SEOK LEE JU-SUEK XIN ZHISHU KIM YOUNG-GYU KIM YOUNG-SOO SONG JAE-YOUNG PARK JIN-WAN GI BEOM HONG LEE JI-HOON YOON HEE-SEOK YOO JI HOON JEON HEE-JEON |
| description | Provided are: a novel pyrrolidine derivative or a pharmaceutically acceptable salt thereof; and a novel pyrrolidine derivative containing the same, which has an effect of inhibiting the aggregation of beta-amyloid protein and/or Tau protein and/or an effect of degrading aggregates of beta-amyloid protein and/or casein. And/or beta-amyloid protein and/or Tau protein related diseases can be prevented and/or treated.
本发明提供一种新型吡咯烷衍生物或其药学上可接受的盐、以及包含其的具有β-淀粉样蛋白和/或Tau蛋白聚集抑制效果、和/或β-淀粉样蛋白和/或酪蛋白的聚集体降解效果、和/或β-淀粉样蛋白和/或Tau蛋白相关疾病预防和/或治疗效果的药物组合物。 |
| format | Patent |
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本发明提供一种新型吡咯烷衍生物或其药学上可接受的盐、以及包含其的具有β-淀粉样蛋白和/或Tau蛋白聚集抑制效果、和/或β-淀粉样蛋白和/或酪蛋白的聚集体降解效果、和/或β-淀粉样蛋白和/或Tau蛋白相关疾病预防和/或治疗效果的药物组合物。</description><language>chi ; eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220826&DB=EPODOC&CC=CN&NR=114945569A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220826&DB=EPODOC&CC=CN&NR=114945569A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KIM DA-YONG</creatorcontrib><creatorcontrib>KIM SUNG-HWAN</creatorcontrib><creatorcontrib>LEE WON-SEOK</creatorcontrib><creatorcontrib>LEE JU-SUEK</creatorcontrib><creatorcontrib>XIN ZHISHU</creatorcontrib><creatorcontrib>KIM YOUNG-GYU</creatorcontrib><creatorcontrib>KIM YOUNG-SOO</creatorcontrib><creatorcontrib>SONG JAE-YOUNG</creatorcontrib><creatorcontrib>PARK JIN-WAN</creatorcontrib><creatorcontrib>GI BEOM HONG</creatorcontrib><creatorcontrib>LEE JI-HOON</creatorcontrib><creatorcontrib>YOON HEE-SEOK</creatorcontrib><creatorcontrib>YOO JI HOON</creatorcontrib><creatorcontrib>JEON HEE-JEON</creatorcontrib><title>Pyrrolidine derivative, and pharmaceutical composition for preventing or treating beta-amyloid or tau protein-related diseases comprising same</title><description>Provided are: a novel pyrrolidine derivative or a pharmaceutically acceptable salt thereof; and a novel pyrrolidine derivative containing the same, which has an effect of inhibiting the aggregation of beta-amyloid protein and/or Tau protein and/or an effect of degrading aggregates of beta-amyloid protein and/or casein. And/or beta-amyloid protein and/or Tau protein related diseases can be prevented and/or treated.
本发明提供一种新型吡咯烷衍生物或其药学上可接受的盐、以及包含其的具有β-淀粉样蛋白和/或Tau蛋白聚集抑制效果、和/或β-淀粉样蛋白和/或酪蛋白的聚集体降解效果、和/或β-淀粉样蛋白和/或Tau蛋白相关疾病预防和/或治疗效果的药物组合物。</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNTjsKwkAUTGMh6h3W3hSiEVJKUKzEwl6e2Yk-2Owub18CXsIzG4MHsJoZ5sNMs_flJRIcW_YwFsI9KfdYGfLWxCdJSzU65ZqcqUMbQ2Ll4E0TxERBD6_sH2ZQKqCR36GUU_tyge1oUDdEg4J9LnCksMZyAiWkcVM4fXuJWsyzSUMuYfHDWbY8Hq7VKUcMN6Q4nPHQW3Ver7fltih25X7zT-YDv5hP8w</recordid><startdate>20220826</startdate><enddate>20220826</enddate><creator>KIM DA-YONG</creator><creator>KIM SUNG-HWAN</creator><creator>LEE WON-SEOK</creator><creator>LEE JU-SUEK</creator><creator>XIN ZHISHU</creator><creator>KIM YOUNG-GYU</creator><creator>KIM YOUNG-SOO</creator><creator>SONG JAE-YOUNG</creator><creator>PARK JIN-WAN</creator><creator>GI BEOM HONG</creator><creator>LEE JI-HOON</creator><creator>YOON HEE-SEOK</creator><creator>YOO JI HOON</creator><creator>JEON HEE-JEON</creator><scope>EVB</scope></search><sort><creationdate>20220826</creationdate><title>Pyrrolidine derivative, and pharmaceutical composition for preventing or treating beta-amyloid or tau protein-related diseases comprising same</title><author>KIM DA-YONG ; KIM SUNG-HWAN ; LEE WON-SEOK ; LEE JU-SUEK ; XIN ZHISHU ; KIM YOUNG-GYU ; KIM YOUNG-SOO ; SONG JAE-YOUNG ; PARK JIN-WAN ; GI BEOM HONG ; LEE JI-HOON ; YOON HEE-SEOK ; YOO JI HOON ; JEON HEE-JEON</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN114945569A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2022</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>KIM DA-YONG</creatorcontrib><creatorcontrib>KIM SUNG-HWAN</creatorcontrib><creatorcontrib>LEE WON-SEOK</creatorcontrib><creatorcontrib>LEE JU-SUEK</creatorcontrib><creatorcontrib>XIN ZHISHU</creatorcontrib><creatorcontrib>KIM YOUNG-GYU</creatorcontrib><creatorcontrib>KIM YOUNG-SOO</creatorcontrib><creatorcontrib>SONG JAE-YOUNG</creatorcontrib><creatorcontrib>PARK JIN-WAN</creatorcontrib><creatorcontrib>GI BEOM HONG</creatorcontrib><creatorcontrib>LEE JI-HOON</creatorcontrib><creatorcontrib>YOON HEE-SEOK</creatorcontrib><creatorcontrib>YOO JI HOON</creatorcontrib><creatorcontrib>JEON HEE-JEON</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KIM DA-YONG</au><au>KIM SUNG-HWAN</au><au>LEE WON-SEOK</au><au>LEE JU-SUEK</au><au>XIN ZHISHU</au><au>KIM YOUNG-GYU</au><au>KIM YOUNG-SOO</au><au>SONG JAE-YOUNG</au><au>PARK JIN-WAN</au><au>GI BEOM HONG</au><au>LEE JI-HOON</au><au>YOON HEE-SEOK</au><au>YOO JI HOON</au><au>JEON HEE-JEON</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Pyrrolidine derivative, and pharmaceutical composition for preventing or treating beta-amyloid or tau protein-related diseases comprising same</title><date>2022-08-26</date><risdate>2022</risdate><abstract>Provided are: a novel pyrrolidine derivative or a pharmaceutically acceptable salt thereof; and a novel pyrrolidine derivative containing the same, which has an effect of inhibiting the aggregation of beta-amyloid protein and/or Tau protein and/or an effect of degrading aggregates of beta-amyloid protein and/or casein. And/or beta-amyloid protein and/or Tau protein related diseases can be prevented and/or treated.
本发明提供一种新型吡咯烷衍生物或其药学上可接受的盐、以及包含其的具有β-淀粉样蛋白和/或Tau蛋白聚集抑制效果、和/或β-淀粉样蛋白和/或酪蛋白的聚集体降解效果、和/或β-淀粉样蛋白和/或Tau蛋白相关疾病预防和/或治疗效果的药物组合物。</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Pyrrolidine derivative, and pharmaceutical composition for preventing or treating beta-amyloid or tau protein-related diseases comprising same |
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