Pyrrolidine derivative, and pharmaceutical composition for preventing or treating beta-amyloid or tau protein-related diseases comprising same

Provided are: a novel pyrrolidine derivative or a pharmaceutically acceptable salt thereof; and a novel pyrrolidine derivative containing the same, which has an effect of inhibiting the aggregation of beta-amyloid protein and/or Tau protein and/or an effect of degrading aggregates of beta-amyloid pr...

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Hauptverfasser: KIM DA-YONG, KIM SUNG-HWAN, LEE WON-SEOK, LEE JU-SUEK, XIN ZHISHU, KIM YOUNG-GYU, KIM YOUNG-SOO, SONG JAE-YOUNG, PARK JIN-WAN, GI BEOM HONG, LEE JI-HOON, YOON HEE-SEOK, YOO JI HOON, JEON HEE-JEON
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:Provided are: a novel pyrrolidine derivative or a pharmaceutically acceptable salt thereof; and a novel pyrrolidine derivative containing the same, which has an effect of inhibiting the aggregation of beta-amyloid protein and/or Tau protein and/or an effect of degrading aggregates of beta-amyloid protein and/or casein. And/or beta-amyloid protein and/or Tau protein related diseases can be prevented and/or treated. 本发明提供一种新型吡咯烷衍生物或其药学上可接受的盐、以及包含其的具有β-淀粉样蛋白和/或Tau蛋白聚集抑制效果、和/或β-淀粉样蛋白和/或酪蛋白的聚集体降解效果、和/或β-淀粉样蛋白和/或Tau蛋白相关疾病预防和/或治疗效果的药物组合物。