Cocktail-type compositions comprising respiratory antibacterial bacteriophages and methods of use thereof

The present invention relates to the field of bacteriophage therapy for the treatment and control of bacterial infections, in particular respiratory bacterial infections such as bacterial pneumonia. More specifically, the present invention relates to novel bacteriophage strains and mixtures thereof,...

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Bibliographische Detailangaben
Hauptverfasser: VOCKERT-REO SANDRA, DA COSTA GARCIA MIGUEL ANGELO, RODRIGUES LEANDRO CLARA ISABEL, MARTINEZ BARBOSA ANA RAQUEL, MARTINS, ANTONIO, F, JONSTIANS, DIRK
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The present invention relates to the field of bacteriophage therapy for the treatment and control of bacterial infections, in particular respiratory bacterial infections such as bacterial pneumonia. More specifically, the present invention relates to novel bacteriophage strains and mixtures thereof, and variants thereof; and methods of using the same to treat and prevent bacterial infections, including respiratory infections caused by, for example, Pseudomonas aeruginosa and/or Klebsiella pneumonia. The mixture may be used alone as a pharmaceutical composition, or further in combination with other therapies, such as antibiotics or other standard and non-standard therapies for respiratory infections. 本发明涉及用于治疗和控制细菌感染,特别是呼吸系统细菌感染如细菌性肺炎的噬菌体疗法领域。更具体地说,本发明涉及新型噬菌体株及其混合物,以及它们的变体;和使用它们治疗和预防细菌感染的方法,该细菌感染包括由例如铜绿假单胞菌和/或克雷伯氏肺炎菌造成的呼吸系统感染。该混合物可单独用作药物组合物,或者进一步与其他疗法(如抗生素或其他用于呼吸系统感染的标准和非标准疗法)联合使用。