Method for constructing antibody complementarity determining region library

The invention relates to a method and a device for constructing an antibody complementarity determining region (CDR) library. And a method, apparatus and computer program product for determining the frequency of occurrence of individual member sequences of an antibody CDR library. By means of the me...

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Bibliographische Detailangaben
Hauptverfasser:	SHENG XIA, WU ZHENGXIAN, QIU YIKAI
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMBINATORIAL CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention relates to a method and a device for constructing an antibody complementarity determining region (CDR) library. And a method, apparatus and computer program product for determining the frequency of occurrence of individual member sequences of an antibody CDR library. By means of the methods, devices and computer program products, antibody CDR libraries having a specific distribution of amino acids at one or more positions can be obtained. 一种构建抗体互补决定区(CDR)文库的方法和装置。以及用于确定抗体CDR文库的各个成员序列出现频率的方法、装置和计算机程序产品。通过所述方法、装置和计算机程序产品能够获得一个或多个位置具有特定氨基酸分布的抗体CDR文库。