Self-assembly material for in-situ construction at wound part as well as preparation method and application of self-assembly material

The invention relates to a self-assembly material constructed in situ at a wound part and a preparation method and application thereof.The self-assembly material constructed in situ at the wound part is composed of a targeting peptide, a self-assembly unit and a signal molecule, the chemical structure of the self-assembly material is shown in the formula (I), R1 is from polypeptide with multiple hydrogen bonds in the molecule, R2 is from polypeptide with multiple hydrogen bonds in the molecule, and R3 is from polypeptide with multiple hydrogen bonds in the molecule. And R2 is from a wound targeting peptide. The self-assembly material can be induced to deform at a wound part and is self-assembled to form a beta-folded nanofiber net structure, so that a peptide net is formed in situ to wind platelets, fibrin and red blood cells, embolism is formed on a wound surface, and the purposes of stopping bleeding and promoting wound healing are achieved. In addition, the self-assembly material can promote migration of f