Nanoarray-based aptamer electrochemical sensor
The invention discloses an aptamer electrochemical sensor based on a nano array, which is characterized in that a gold-plated polyacrylonitrile (Au (at) PAN) nano array is used as an electrode, an aptamer is covalently bound on the surface of the electrode through an Au-S bond, an obtained modified...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention discloses an aptamer electrochemical sensor based on a nano array, which is characterized in that a gold-plated polyacrylonitrile (Au (at) PAN) nano array is used as an electrode, an aptamer is covalently bound on the surface of the electrode through an Au-S bond, an obtained modified electrode is used as a working electrode, and a three-electrode system is adopted to form the aptamer electrochemical sensor for selectively identifying an object to be detected. According to the invention, the ordered nanostructure is combined with the aptamer electrochemical sensor, and the rapid, sensitive and selective detection of the to-be-detected object is realized by using the specific selection of the aptamer, the rapid response of the electrochemical sensor and the signal enhancement function of the nanostructure.
本发明公开了一种基于纳米阵列的适配体电化学传感器,是以镀金聚丙烯腈(Au@PAN)纳米阵列为电极,通过Au-S键将适配体共价结合在电极表面,获得的修饰电极即为工作电极,采用三电极体系,构成用于选择性识别待检测物的适配体电化学传感器。本发明将有序纳米结构与适配体电化学传感器相结合,利用适配体的特异性选择、电化学传感器的响应快速以及纳米结构的信号增强功能,实现对待检测物的快速、灵敏、选择 |
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