Gold-platinum complex chiral nanoparticle for treating oral squamous cell carcinoma
The invention belongs to the field of preparation of nano-drugs for tumor treatment, and provides a preparation method of gold-platinum complex chiral nanoparticles capable of treating oral squamous cell carcinoma, which comprises the following steps: dissolving a certain amount of chloroauric acid...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention belongs to the field of preparation of nano-drugs for tumor treatment, and provides a preparation method of gold-platinum complex chiral nanoparticles capable of treating oral squamous cell carcinoma, which comprises the following steps: dissolving a certain amount of chloroauric acid and chloroplatinic acid in a solvent, reacting at low temperature, adding a carbon-based nano-catalyst, uniformly stirring and preserving heat. And the added cationic surface active agent is subjected to medium-temperature reaction. Dropwise adding a chiral modification inducer by adopting a micro-fluidic technology, and carrying out high-temperature reaction; and washing and drying the reaction precipitate. The method is simple in process, high in yield and easy to realize industrial mass production. The particle size of the prepared chiral nanoparticles is 0.1-1 micron, and the surfaces of the chiral nanoparticles have peony patterns and emit red fluorescence under excitation of an ultraviolet lamp. The killing e |
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