Streptococcus suis three-component subunit vaccine and preparation method thereof

The invention discloses a streptococcus suis three-component subunit vaccine and a preparation method thereof, the vaccine contains an antigen HP0526, an antigen HP1130, an antigen HP0918 and an adjuvant, the amino acid sequence of the antigen HP0526 is shown as SEQ ID NO.1, the amino acid sequence...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	LIANG GONG, TANG XIBIAO, HUANG YING, ZHOU MINGGUANG, LONG YUNZHI, XU GAOYUAN, LI QIANQIAN, SONG WENBO, YANG LIU, YU DAOBING, HUANG CHAO
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The invention discloses a streptococcus suis three-component subunit vaccine and a preparation method thereof, the vaccine contains an antigen HP0526, an antigen HP1130, an antigen HP0918 and an adjuvant, the amino acid sequence of the antigen HP0526 is shown as SEQ ID NO.1, the amino acid sequence of the antigen HP1130 is shown as SEQ ID NO.2, and the amino acid sequence of the antigen HP0918 is shown as SEQ ID NO.3. The invention further discloses a preparation method of the streptococcus suis three-component subunit vaccine. The preparation method of the vaccine comprises the following steps: obtaining an antigen HP0526, an antigen HP1130 and an antigen HP0918 by using gene cloning, protein expression and purification technologies, and mixing the antigen HP0526, the antigen HP1130 and the antigen HP0918 with an adjuvant to prepare the streptococcus suis three-component subunit vaccine. The three-component subunit vaccine can be used for protecting pigs against infection of streptococcus suis serum types 2,