Polysaccharide carbon nanogel, and preparation method and pharmaceutical composition thereof

The invention provides nano glue with anticoagulation, antitumor and antioxidant activity, which comprises graphene-like nanosheets and polysaccharide, and the graphene-like nanosheets and the polysaccharide are compounded to form a cross-linked supramolecular structure. The invention also provides a method for preparing the nanogel. The method comprises the step of carbonizing the polysaccharide through dry heating. By means of the heating process, at least one part of polysaccharide is converted into graphene-like nanosheets, so that the phenol polysaccharide nano-gum embedded with the graphene-like nanosheets is formed, and the phenol polysaccharide nano-gum has an excellent polyphenol structure and high binding affinity to thrombin, can inhibit tumor metastasis and can be used for preparing an anti-tumor or anti-coagulation pharmaceutical composition. 本发明提供一种具有抗凝血、抗肿瘤和抗氧化活性的纳米胶，其包括类石墨烯纳米片及多糖，且其等经复合以形成交联的超分子结构。本发明另提供一种制备纳米胶的方法，其包括透过干式加热使多糖碳化。藉此加热过程，使至少一部分多糖被转化成类石墨烯纳米片，从而形成类石墨烯纳米片嵌入的酚多糖纳米胶，其具有优异的多酚结构及对凝血酶的高