Molecular marker for detecting tRF type gastric cancer in plasma and application of molecular marker in preparation of gastric cancer auxiliary diagnosis kit

The invention relates to a molecular marker for detecting tRF type gastric cancer in plasma and application of the molecular marker in preparation of a gastric cancer auxiliary diagnosis kit, and is characterized in that the molecular marker comprises reagents used for detecting tRF-18-79MP9P04, tRF...

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Hauptverfasser: YU XIUCHONG, XIE YAOYAO, WENG QIUYAN, SONG XUEMEI, GUO JUNMING, ZHANG SHUANGSHUANG
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to a molecular marker for detecting tRF type gastric cancer in plasma and application of the molecular marker in preparation of a gastric cancer auxiliary diagnosis kit, and is characterized in that the molecular marker comprises reagents used for detecting tRF-18-79MP9P04, tRF-30-87R8WP9N1EWJ, tRF-21-V2989UV3B and tRF-33-P4R8YP9LON4VDP in a plasma sample. The kit disclosed by the invention has the advantages that tRF-18-79MP9P04, tRF-30-87R8WP9N1EWJ, tRF-21-V2989UV3B and tRF-33-P4R8YP9LON4VDP are combined to be used as markers for auxiliary diagnosis of the early gastric cancer, and absolute quantitative detection of target molecules and screening and identification of the early gastric cancer can be accurately completed. 本发明涉及一种检测血浆中tRF型胃癌分子标记物以及在制备胃癌辅助诊断试剂盒的应用,其特征在于:包括用于检测血浆样本中tRF-18-79MP9P04、tRF-30-87R8WP9N1EWJ、tRF-21-V2989UV3B以及tRF-33-P4R8YP9LON4VDP的试剂,与现有技术相比,本发明的优点在于:本发明的试剂盒将tRF-18-79MP9P04、tRF-30-87R8WP9N1EWJ、tRF-21-V2989UV3B以及tRF-33-P4R8YP9LON4VDP联合作为早期胃癌辅助诊断的标志物,能准确地完成靶标分子的绝对定量