Application of glycyrrhizin in improvement of prostatic cancer

The invention discloses an application of glycyrrhizin in improvement of prostatic cancer. Wherein the glycyrrhizin can improve the prostatic cancer by promoting the apoptosis of drug-resistant cells for chemotherapy of the prostatic cancer; furthermore, the glycyrrhizin promotes the apoptosis of dr...

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Bibliographische Detailangaben
Hauptverfasser:	NIE LIHONG, MIAN YUCHEN, YANG WEIXIN, ZHOU QIFEI, YANG BOYA, WANG ZHENWEI, AN KANGJIE, TIAN GUOLIN, LI YAJIE, ZHAO RUINING, LIU SHIYU
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention discloses an application of glycyrrhizin in improvement of prostatic cancer. Wherein the glycyrrhizin can improve the prostatic cancer by promoting the apoptosis of drug-resistant cells for chemotherapy of the prostatic cancer; furthermore, the glycyrrhizin promotes the apoptosis of drug-resistant cells for chemotherapy of the prostatic cancer by inhibiting the expression of ABCB1, so that the prostatic cancer is improved; furthermore, the glycyrrhizin promotes the apoptosis of drug-resistant cells for prostate chemotherapy by inhibiting the expression of an ABCB1 transporter, so that the prostate cancer is improved; furthermore, the glycyrrhizin inhibits the expression of an ABCB1 transporter through a PI3K/AKT/NF-kappa B signal channel so as to promote the apoptosis of drug-resistant cells for chemotherapy of the prostatic cancer, thereby improving the prostatic cancer. According to the technical scheme disclosed by the invention, the apoptosis of the drug-resistant cells for chemotherapy of t