Preparation method and application of precious metal (at) MOF nanoparticle antibiotic substitute

The invention discloses a preparation method of a precious metal (at) MOF nanoparticle antibiotic substitute, precious metal nanoparticles are loaded in an MOF material to prepare precious metal (at) MOF nanoparticles, and the obtained precious metal (at) MOF nanoparticles serve as the antibiotic substitute to be applied to feed. The compound has the advantages of being excellent in antibacterial property, high in pH stability, good in biocompatibility, high in biological safety and the like, can efficiently remove intestinal pathogens and prevent animal diseases, has the effect of supplementing microelements, and can be used as an antibiotic substitute in feed. 本申请公开了一种贵金属@MOF纳米颗粒抗生素替代剂的制备方法，通过在MOF材料中负载贵金属纳米颗粒，制备了贵金属@MOF纳米颗粒，得到的贵金属@MOF纳米颗粒作为抗生素替代剂在饲料中的应用，具有抗菌性优异、pH稳定性高、生物相容性好、生物安全性高等优点，能高效去除肠道病原菌，预防动物疾病，同时具备补充微量元素的作用，可作为抗生素替代剂用于饲料中。