Methods and compositions for treating cancer using multiple ligand-conjugated nanoparticles to bind to receptors on NK cells

The present invention provides methods and compositions comprising a particle comprising at least one first targeting agent capable of binding a first target on the surface of an NK cell, and at least one second targeting agent capable of binding a second target on the surface of a cancer cell, the second targeting agent is different from the first targeting agent. 本发明提供方法和组合物，组合物包含颗粒，颗粒包含至少一个第一靶向试剂，第一靶向试剂能够结合NK细胞表面上的第一靶标，以及至少一个第二靶向试剂，第二靶向试剂能够结合癌细胞表面上的第二靶标，其中，所述第二靶向试剂不同于所述第一靶向试剂。