Salvianolic acid B as well as powder inhalation capsule and preparation method thereof

The invention relates to salvianolic acid B as well as a powder inhalation capsule and a preparation method thereof. The salvia miltiorrhiza medicinal material is used as a raw material, extraction process conditions are provided in a targeted manner, separation and purification operation and spray drying are optimized, extraction and recrystallization treatment are combined, the yield and purity of the salvianolic acid B are improved, and the prepared salvianolic acid B is high in purity, has ideal crystal granularity and distribution, can be well used for preparing salvianolic acid B powder inhalation capsules, and has good application prospects. The bioavailability of the salvianolic acid B is improved, and a wider application way and prospect are provided for the salvianolic acid B. 本发明涉及一种丹酚酸B及其粉雾剂胶囊和制备方法。本发明以丹参药材为原料，针对性提供浸提工艺条件，并优化分离纯化操作和喷雾干燥，结合萃取，重结晶处理，提高丹酚酸B的收率和纯度，制备得到的丹酚酸B纯度高，具有理想的结晶粒度和分布，可很好地用于制备丹酚酸B粉雾剂胶囊，提高其生物利用度，并为丹酚酸B提供更为广阔的应用途径和前景。