Recombinant G factor derived from tachypleus tridentatus and method for measuring beta-glucan using same

The present invention addresses the problem of providing a Tachypleus tridentatus-derived G factor that is activated in a beta-glucan-dependent manner, and a method for measuring a beta-glucan with high sensitivity using the G factor. The present invention relates to: a heterodimer; a method for measuring a beta-glucan using the heterodimer; and a kit for measuring a beta-glucan, which contains the heterodimer. The heterodimer is a combination of a G factor alpha subunit containing an amino acid sequence identical to or substantially identical to the amino acid sequence represented by SEQ ID NO: 2 or SEQ ID NO: 4 and a G factor beta subunit containing an amino acid sequence identical to or substantially identical to the amino acid sequence represented by any of SEQ ID NO: 6, 8, 10, 12, 14 or 16. 本发明的课题在于提供被β-葡聚糖依赖性激活的源自鲎的G因子及使用该G因子的高灵敏度的β-葡聚糖的测定方法。本发明涉及一种"异源二聚体、使用该异源二聚体的β-葡聚糖的测定方法及包含该异源二聚体的β-葡聚糖测定用试剂盒，该异源二聚体为含有与序列号2或序列号4表示的氨基酸序列相同或实质上相同的氨基酸序列的G因子α亚基和含有与序列号6、8、10、12、14或16中的任一个表示的氨基酸序列相同或实质上相同的氨基酸序列的G因子β亚基的组合"。