Independent control of electrical stimulation amplitude of electrodes for delivery of electrical stimulation therapy

Techniques are described for a medical device that delivers electrical stimulation using a current or voltage regulator having an adjustable main amplitude. An exemplary method includes receiving, via a programmer for an electrical stimulator, a user input indicative of a desired current amplitude; and selecting either the first fractional adjustment or the second fractional adjustment as a target adjustment for achieving the desired current amplitude. A neuromodulation system includes: a first electrode; a second electrode; a stimulation generator configured to deliver a first stimulation pulse to the first electrode and a second stimulation pulse to the second electrode, where a first current amplitude of the first stimulation pulse is a first fraction of the main amplitude and a second current amplitude of the second stimulation pulse is a second fraction of the main amplitude; and a processor configured to: generate an initial instruction for the stimulation generator to: (i) deliver the first analog puls