Genome editing in bacteroides

Provided herein are compositions and methods for genome editing of a species of Bacteroides (Bacteroides). The RNA-guided nucleobase modification system is engineered to target a specific locus in chromosomal DNA of a target bacterial cell, wherein the genome of the target bacterial cell can be modi...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	ZHANG, ZAIHUI, EASTLUND ERIK, DAVIS GREGORY DALE
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Provided herein are compositions and methods for genome editing of a species of Bacteroides (Bacteroides). The RNA-guided nucleobase modification system is engineered to target a specific locus in chromosomal DNA of a target bacterial cell, wherein the genome of the target bacterial cell can be modified. 本文提供了用于拟杆菌属(Bacteroides)物种的基因组编辑的组合物和方法。RNA引导的核碱基修饰系统被改造为靶向靶细菌细胞的染色体DNA中的特定基因座，其中可以修饰靶细菌细胞的基因组。