3-(hydroxybenzyl) phthalide compound, and preparation method and application thereof

The invention discloses a 3-(hydroxybenzyl) phthalide compound (I), pharmaceutically acceptable salts thereof, a preparation method thereof, a pharmaceutical composition and application of the 3-(hydroxybenzyl) phthalide compound in preparation of drugs for treating and/or preventing nervous system related diseases. Comprising but not limited to vascular dementia, Alzheimer's disease, Parkinson's disease, Huntington's disease, HIV-related dementia, multiple sclerosis, amyotrophic lateral sclerosis, neuropathic pain, ischemic cerebral apoplexy, hemorrhagic cerebral apoplexy, nerve injury caused by cerebral trauma and other diseases; . 本发明公开了一类3-(羟基苄基)苯酞类化合物（I）及其药学上可接受的盐、其制备方法、药物组合物和在制备治疗和/或预防神经系统相关疾病药物中的用途，包括但不限于血管性痴呆、阿尔茨海默氏病、帕金森氏症、亨廷顿氏症、HIV相关痴呆症、多发性硬化症、肌萎缩侧索硬化症、神经性疼痛、缺血性脑卒中、出血性脑卒中、以及脑外伤引起的神经损伤等疾病；。