Organ deformation compensation for medical image registration

Systems and methods for medical image registration are provided. A first input medical image and a second input medical image of one or more anatomical objects are received. For each respective anatomical object of the one or more anatomical objects: detecting a region of interest comprising the respective anatomical object in one of the first input medical image or the second input medical image, extracting the region of interest from the first input medical image and the second input medical image, and determining a motion distribution of the respective anatomical object from one of the region of interest extracted from the first input medical image or the region of interest extracted from the second input medical image using a motion model specific to the respective anatomical object. The first input medical image and the second input medical image are registered based on a motion profile of each respective anatomical object of the one or more anatomical objects to generate a fused image. 提供了用于医学图像配准的系统和方法