Functionalized heterocyclic compounds as modulators of interferon gene stimulants (STINGs)

The present invention relates to compound-linker constructs and antibody-drug-conjugates of compounds of formula (I) that are useful as modulators of STING (Stimulator of Interferon Gene). 本发明涉及可用作STING(干扰素基因刺激物)的调节剂的式(I)化合物的化合物-连接基构建体和抗体-药物-缀合物。...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	FABRICIUS CHARLES-HENRY, ZWIRTNIA GARY W, WOJNOWSKI, MARK, ZAWAZKA MACIEJ I, SINAK DAVID J, RAJDA ANURAG, ZUCHOWICZ KRZYSZTOF, MAHAJAN TUSHAR R, RICE MICHAEL W, GIBAS ANDREW J, LAZIMIERSKI, AURELIA, TANGIRALA SRINIVAS REDDY, STASI LUIGI PIERO, DUDEK LINDA P, ROGACKI MICHAEL K
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The present invention relates to compound-linker constructs and antibody-drug-conjugates of compounds of formula (I) that are useful as modulators of STING (Stimulator of Interferon Gene). 本发明涉及可用作STING(干扰素基因刺激物)的调节剂的式(I)化合物的化合物-连接基构建体和抗体-药物-缀合物。