Research method of panaxadiol

The invention discloses a research method of panoxadiol, and belongs to the technical field of research of (20R)-panoxadiol, and the technical key point is that the research method comprises the research steps of (20R)-panoxadiol: step 1, excavating material basis, target spots and pathways of ginse...

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Hauptverfasser: ZHANG MING, CHEN LI, GUAN FENGYING, LYU YUQING, FENG JIANSHU
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a research method of panoxadiol, and belongs to the technical field of research of (20R)-panoxadiol, and the technical key point is that the research method comprises the research steps of (20R)-panoxadiol: step 1, excavating material basis, target spots and pathways of ginseng for resisting obesity and complications thereof through network pharmacology; 2, studying the lipid-lowering and weight-losing curative effect and mechanism of the (20R)-panoxadiol on the high-fat fed mouse; 3, researching the relationship between the inhibition of (20R)-panoxadiol on fat cell hypertrophy and the cAMP/PKA pathway through experiments; 4, (20R)-panoxadiol is used for researching the lipid-lowering and weight-losing mechanism of ob/ob obese mice by regulating and controlling a beta2/cAMP/PKA pathway; 5, observing the efficacy of (20R)-panoxadiol for preventing and treating non-alcoholic fatty liver of high-fat induced obese mice and ob/ob obese mice, and primarily probing the mechanism of the (20R)