Loratadine composition and preparation method thereof
The invention belongs to the technical field of pharmaceutical preparations, and particularly relates to a loratadine composition and a preparation method thereof. The invention provides a novel loratadine composition, which is prepared from the following components in parts by weight: 1.0 to 3.0 pa...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention belongs to the technical field of pharmaceutical preparations, and particularly relates to a loratadine composition and a preparation method thereof. The invention provides a novel loratadine composition, which is prepared from the following components in parts by weight: 1.0 to 3.0 parts of loratadine, 1 to 1.5 parts of benzoic acid, 90 to 120 parts of glycerol, 70 to 90 parts of propylene glycol and 4.0 to 6.0 parts of anhydrous citric acid. The loratadine syrup product prepared by using the formula is not layered after being placed for a long time, the impurity content is slowly increased, and the loratadine syrup product has good stability. Furthermore, the invention also optimizes the preparation process of the loratadine syrup, and by optimizing the dissolving and mixing sequence of the raw materials, the dissolving rate is effectively improved, and the stability of the loratadine syrup product can be further improved. Therefore, the invention has a good application prospect in clinical us |
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