High-performance processable hydrogel as well as preparation method and application thereof
The invention discloses a high-performance processable hydrogel and a preparation method and application thereof, the hydrogel comprises a processable polymer hydrogel matrix and an interpenetrating network structure and/or a semi-interpenetrating network structure formed in the matrix based on a di...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention discloses a high-performance processable hydrogel and a preparation method and application thereof, the hydrogel comprises a processable polymer hydrogel matrix and an interpenetrating network structure and/or a semi-interpenetrating network structure formed in the matrix based on a dispersion system of alginate and a biological ceramic material, therefore, the hydrogel can entrap biological ceramic material particles with bone repair inducing capacity and other types of bioactive substances such as drugs, bioactive molecules or cells, so that the hydrogel can load and convey the bioactive substances. And by reasonably optimizing the ratio of the components in the gel network, the mechanical properties of the gel network are adjusted, the differentiation capability of irregular force-bearing osteoblasts is induced and supported, and mineralization is promoted. Therefore, the hydrogel obtained by the invention has a relatively high application prospect in the fields of disease treatment and tissu |
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