Preparation method of skin-core structure electrostatic spinning nanofiber

The invention relates to a preparation method of skin-core structure electrostatic spinning nanofibers, which comprises the following steps: firstly, carrying out ion exchange reaction on organic cations and montmorillonite to obtain organic montmorillonite, then adding the organic montmorillonite and a polymer into hexafluoroisopropanol, and uniformly mixing to obtain a mixed solution; the skin-core structure electrostatic spinning nanofiber is prepared through blending electrostatic spinning; the skin layer of the prepared skin-core structure electrostatic spinning nanofiber is a polymer, and the core layer is organic montmorillonite; the organic montmorillonite is composed of montmorillonite and organic cations distributed among montmorillonite layers. The fiber with the skin-core structure and the nano structure is prepared by adopting a blending electrostatic spinning method, the preparation method is simple to operate and low in cost, and good economic benefits can be brought; and the drug can be loaded