Purification method of tetanus immune globulin and affinity chromatography filler of tetanus immune globulin

The invention relates to the technical field of purification of human immune globulin, in particular to a purification method of tetanus immune globulin and affinity chromatography filler of the tetanus immune globulin. The purification method of the tetanus immune globulin comprises the following steps: carrying out affinity chromatography treatment on a product by using a chromatographic column; the chromatographic column is filled with a chromatographic filler, and the chromatographic filler is coupled with an affinity substance for specifically binding with a tetanus antibody. The affinity chromatography filler comprises the following raw materials: a cross-linked agarose-based medium and ligands, wherein the ligands comprise a tetanus toxoid finished product, a tetanus toxoid semi-finished product and a tetanus toxoid stock solution. According to the technical scheme, the technical problem that a method for effectively enriching tetanus antibodies in plasma is lacked in the prior art can be solved. The t