Methods and combinations for treating cancer using immune checkpoint inhibitor antibodies

The present disclosure relates to methods, compositions, and combinations for treating cancer. In particular, the disclosure relates to methods comprising administering to a subject in need thereof at least one of an anti-CTLA-4 antibody or antigen-binding fragment and an anti-PD-L1 antibody or antigen-binding fragment thereof. The disclosure also relates to combinations comprising at least one of an anti-CTLA-4 antibody or antigen binding fragment and an anti-PD-L1 antibody or antigen binding fragment thereof. 本披露内容涉及用于治疗癌症的方法、组合物和组合。具体地，本披露内容涉及包括向有需要的受试者施用抗CTLA-4抗体或抗原结合片段和抗PD-L1抗体或其抗原结合片段中的至少一种的方法。本披露内容还涉及包含抗CTLA-4抗体或抗原结合片段和抗PD-L1抗体或其抗原结合片段中的至少一种的组合。