Application of gene regulator in preparation of liver cancer metastasis medicine

The invention provides application of a gene regulator in preparation of a liver cancer metastasis medicine, and belongs to the technical field of biology. The biomarker provided by the invention is an ENST00000415932.1 gene, and experiments find that the ENST00000415932.1 gene is in low expression...

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Sprache:chi ; eng
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Zusammenfassung:The invention provides application of a gene regulator in preparation of a liver cancer metastasis medicine, and belongs to the technical field of biology. The biomarker provided by the invention is an ENST00000415932.1 gene, and experiments find that the ENST00000415932.1 gene is in low expression in peripheral blood mononuclear cells of a liver cancer patient, and the ENST00000415932.1 gene has a relatively high diagnostic value when being used for diagnosis. Moreover, the invention finds that invasion of liver cancer cells can be effectively inhibited by overexpressing the ENST00000415932.1 gene in the liver cancer cells, so that the plasmid for promoting overexpression of the ENST00000415932.1 gene can be used for preparing the medicine for treating liver cancer metastasis. 本发明提供了一种基因调节剂在制备肝癌转移药物中的应用,属于生物学技术领域。本发明所提供的生物标志物为ENST00000415932.1基因,本发明通过实验发现,ENST00000415932.1基因在肝癌患者的外周血单个核细胞中低表达,而且将ENST00000415932.1基因用于诊断时具有较高的诊断价值。而且,本发明发现,通过在肝癌细胞中过表达ENST00000415932.1基因可以有效的抑制肝癌细胞的侵袭,因此可以将促进ENST00000415932.1基因