High-concentration loading gel of adriamycin medicine and preparation method of high-concentration loading gel

The invention discloses a high-concentration doxorubicin drug loaded gel and a preparation method thereof. The high-concentration doxorubicin drug loaded gel is formed by co-assembling a hybrid dual-network gel carrier and a target drug doxorubicin hydrochloride in a one-pot system, the hybrid dual-network gel comprises a small molecular gelling agent component 9-fluorenylmethoxycarbonyl-L-phenylalanine and a polymer gelling agent component sodium alginate, a broad-spectrum cancer chemotherapy drug doxorubicin is taken as a loading target, the doxorubicin is pre-dissolved in different precursor solutions, then the precursor solutions are gradually added to participate in the assembling and forming process of a gel network, and the hybrid dual-network gel is obtained. According to the present invention, the controllable loading of the high-concentration DOX drug is achieved, the maximum loading capacity can achieve 60 mg/mL, the maximum loading rate can achieve 75%, the preparation method is simple and economi