6-dimethylaminomethyl-1-phenyl-cyclohexane compounds as pharmaceutical active ingredients
6-Dimethylaminomethyl-1-phenyl cyclohexane derivs. of formula (I) are new: R = H, OH, Cl or F; R , R = H, 1-4C alkyl, benzyl, CF3, OH, OCH2Ph, 1-4C alkoxy, Cl or F; R = H, Me, PO(1-4C alkoxy)2, CO(1-5C alkoxy), CO-NH-C6H4-(1-3C alkyl), CO-C6H4-R , CO-(1-5C alkyl), CO-CHR -NHR or opt. substd. pyridyl...
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Sprache: | eng |
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Zusammenfassung: | 6-Dimethylaminomethyl-1-phenyl cyclohexane derivs. of formula (I) are new: R = H, OH, Cl or F; R , R = H, 1-4C alkyl, benzyl, CF3, OH, OCH2Ph, 1-4C alkoxy, Cl or F; R = H, Me, PO(1-4C alkoxy)2, CO(1-5C alkoxy), CO-NH-C6H4-(1-3C alkyl), CO-C6H4-R , CO-(1-5C alkyl), CO-CHR -NHR or opt. substd. pyridyl, thienyl, thiazolyl or phenyl; R = OC(O)-(1-3C alkyl) in ortho position, or CH2-N(R )2 in meta- or para-position; R = 1-4C alkyl; or NR R = 4-morpholino; R , R = H or 1-6C alkyl; provided that: (i) one of R , R = H; (ii) when R and R = H, then R is not Me if R = H, OH or Cl; and (iii) R is not H when R = OH. |
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