Method for preparing 1, 3-propylene glycol through biotransformation

The invention relates to a method for preparing 1, 3-propylene glycol through biotransformation, which is characterized in that the fermentation process is divided into an initial fermentation stage, a fermentation adjustment stage and a later fermentation stage, the initial fermentation stage refers to inoculating a zymophyte seed solution into a fermentation culture medium, and fermentation culture is started under a micro-aerobic condition; the fermentation adjustment period refers to adding yeast liquid when the production rate of the 1, 3-propylene glycol is lower than 1g. L . H along with fermentation, and switching back to the culture mode of the initial fermentation period after the concentration of the symbolic by-product is reduced to a certain degree, and the time is the later fermentation period until the fermentation is finished. According to the method disclosed by the invention, the problem of by-product inhibition in a micro-aerobic mode is solved by utilizing exogenous substrate le