Organic matter for improving luminous intensity of alkaline phosphatase substrate, preparation method of organic matter and enhanced luminescence agent
The invention relates to the technical field of chemical synthesis, in particular to an organic matter for improving the luminous intensity of an alkaline phosphatase substrate, a preparation method of the organic matter and an enhanced luminous agent. The structural formula of the organic matter co...
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Zusammenfassung: | The invention relates to the technical field of chemical synthesis, in particular to an organic matter for improving the luminous intensity of an alkaline phosphatase substrate, a preparation method of the organic matter and an enhanced luminous agent. The structural formula of the organic matter comprises a fluorescein luminous group framework, an amino acid residue bridging structure at least containing two amino groups and an alkane side chain connected with the amino acid residue bridging structure. According to the present invention, the luminescent intensity of the alkaline phosphatase substrate, especially the 1, 2-dioxane derivative AMPPD, can be effectively improved so as to improve the sensitivity of the chemiluminescence detection.
本发明涉及化学合成技术领域,具体而言,涉及用于提升碱性磷酸酶底物发光强度的有机物及其制备方法和增强发光剂。该有机物的结构式包括荧光素发光基团骨架、至少含有2个氨基的氨基酸残基侨联结构以及与氨基酸残基侨联结构连接的烷烃侧链。其可以有效提升碱性磷酸酶底物,特别是1,2-二氧环已烷衍生物AMPPD的发光强度,继而提升化学发光检测的灵敏度。 |
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