Green method for synthesizing compound containing biaryl structure through Suzuki coupling reaction
The invention discloses a green method for synthesizing a compound containing a biaryl structure through a Suzuki coupling reaction. Compared with the conventional anhydrous aprotic solvent, the organic solvent disclosed by the invention is selected from etherate of dihydric alcohol, so that the gen...
Gespeichert in:
Hauptverfasser: | , , , , |
---|---|
Format: | Patent |
Sprache: | chi ; eng |
Schlagworte: | |
Online-Zugang: | Volltext bestellen |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
Zusammenfassung: | The invention discloses a green method for synthesizing a compound containing a biaryl structure through a Suzuki coupling reaction. Compared with the conventional anhydrous aprotic solvent, the organic solvent disclosed by the invention is selected from etherate of dihydric alcohol, so that the generation of reaction byproducts can be effectively reduced, the reaction yield is higher, the product purity is higher, and the subsequent application of the product is not influenced; the product can be separated from a reaction system more easily, so that the economic cost and the time cost of post-treatment are reduced; the solvent used in the method has the characteristics of high flash point and no odor, so that the risk is lower, and the method is more in line with the green and environment-friendly requirements; therefore, the method for synthesizing the compound containing the biaryl structure through the Suzuki coupling reaction is favorable for realizing industrial production and has extremely high industr |
---|