Special thermophilic bacteria for catalytic production of alpha-ketoglutaric acid and catalytic production method

The invention discloses a special thermophilic bacterium for catalytic production of alpha-ketoglutaric acid and a catalytic production method. The strain is Streptomyces sp.TC2303 and is preserved in the China Center for Type Culture Collection on December 27, 2021, the preservation date is Decembe...

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Bibliographische Detailangaben
Hauptverfasser: LIU JIAYIN, YU ZHAOTAO, LI JIANBO, YU YOULIANG, XU FEI, JIA QINGFU, CHEN XIANZHONG, XU HENGDE
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a special thermophilic bacterium for catalytic production of alpha-ketoglutaric acid and a catalytic production method. The strain is Streptomyces sp.TC2303 and is preserved in the China Center for Type Culture Collection on December 27, 2021, the preservation date is December 27, 2021, and the preservation number is CCTCC (China Center for Type Culture Collection) NO: M20211682. The culture and fermentation conditions of the strain Streptomyces sp.TC2303 provided by the invention are both about 45 DEG C, the fermentation time is only 24 hours, and the fermentation time is short; according to the present invention, the fermentation broth can be used to catalyze L-glutamic acid at the temperature of 45-56 DEG C to produce alpha-ketoglutaric acid, the conversion process temperature is more than 45 DEG C, the catalysis temperature is far higher than the prior art, the total reaction time is only 18 h, the catalysis process is not easily subjected to bacterial contamination, and the method