Application of piptanol in preparation of medicine for preventing and treating Alzheimer's disease

The invention discloses an application of fengquinol in preparation of a medicine for preventing and treating senile dementia disease, which discovers that fengquinol has a remarkable protective effect on PC-12 cell injury induced by A beta 25-35 through experimental research for the first time, and can play a role by enhancing the autophagy level of cells; further in-vivo experiments of animals prove that the pipinoquinol can remarkably improve the cognitive function of A beta 25-35 induced mice and improve pathological changes of the brain, can be conveniently prepared into various medicine dosage forms, is convenient to clinically use and is used for preventing and treating the Alzheimer's disease. 本发明公开了风藤奎醇在制备防治老年痴呆疾病药物中的应用，本发明通过实验研究首次发现风藤奎醇对于Aβ25-35诱导的PC-12细胞损伤具有显著的保护作用，并可通过增强细胞的自噬水平发挥作用，进一步在动物体内实验证实风藤奎醇可显著改善Aβ25-35诱导小鼠的认知功能并改善脑部的病理变化，且可方便制备成多种药物剂型，方便临床使用，用于防治老年痴呆症。