Polypeptide and anti-phosphatidylinositol proteoglycan 3 antibody thereof

The invention discloses a polypeptide and an anti-glypican 3 antibody thereof. The polypeptide comprises at least one of amino acid sequences shown as SEQ ID NO: 4, 6, 8, 10, 12, 14, 16, 18, 20, 22, 24, 26, 28, 30, 32, 34, 36, 38, 40, 42, 44 and 46. The antibody can inhibit GPC3 positive cell prolif...

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Bibliographische Detailangaben
Hauptverfasser: JIANG XIAOMING, LIN HAOFENG, YAO TIANQI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a polypeptide and an anti-glypican 3 antibody thereof. The polypeptide comprises at least one of amino acid sequences shown as SEQ ID NO: 4, 6, 8, 10, 12, 14, 16, 18, 20, 22, 24, 26, 28, 30, 32, 34, 36, 38, 40, 42, 44 and 46. The antibody can inhibit GPC3 positive cell proliferation and has the potential of being used for preparing cancer treatment drugs. 一种多肽及其抗磷脂酰肌醇蛋白聚糖3抗体,所述多肽包含如SEQ ID NO:4、6、8、10、12、14、16、18、20、22、24、26、28、30、32、34、36、38、40、42、44、46所示氨基酸序列中的至少一种。该抗体可抑制GPC3阳性细胞增殖,具有可用于制备癌症治疗药物的潜力。