Synthesis method of 2-thiopheneacetic acid

The invention belongs to the technical field of fine chemical engineering, and particularly relates to a synthetic method of 2-thiopheneacetic acid. The method comprises the following steps: by taking thiophene as a raw material, carrying out Friedel-Crafts alkylation reaction under the action of a sulfonic functionalized ionic liquid as a catalyst through an alkylating agent, and carrying out hydrolytic acidification on a reactant to obtain the 2-thiopheneacetic acid. The method has the advantages of cheap raw materials, simple process, small amount of three wastes and high safety. The product is good in quality, high in yield and suitable for industrial production. 本发明属于精细化工技术领域，具体涉及一种2-噻吩乙酸的合成方法。以噻吩为原料经烷基化剂，在磺酸基功能化离子液体作为催化剂的作用下通过傅克烷基化反应，反应物经水解酸化，即得2-噻吩乙酸。本发明方法原料廉价，工艺简单，三废量少，安全性高。产品质量好，收率高，适合工业化生产。