Anti-CD96 antibodies and methods of use thereof

The present disclosure provides antibodies that specifically bind to CD96 (e.g., human CD96) and antagonize CD96 function. Also provided are pharmaceutical compositions comprising these antibodies, nucleic acids encoding these antibodies, expression vectors, and host cells for making these antibodie...

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Bibliographische Detailangaben
Hauptverfasser:	IGNATOVICH OLGA, BRIAND EMMANUEL CHRISTIAN PAUL, BUSHELL KEVIN M, CHAND DHIRAJ SHANTILAL, RAMSEY NICHOLAS A, GOMBOS ROBERT B
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present disclosure provides antibodies that specifically bind to CD96 (e.g., human CD96) and antagonize CD96 function. Also provided are pharmaceutical compositions comprising these antibodies, nucleic acids encoding these antibodies, expression vectors, and host cells for making these antibodies, as well as methods of using these antibodies to treat subjects. 本公开提供了特异性结合至CD96(例如，人CD96)以及拮抗CD96功能的抗体。还提供了包含这些抗体、编码这些抗体的核酸、表达载体和用于制备这些抗体的宿主细胞的药物组合物，以及使用这些抗体来治疗受试者的方法。