Rapid separation type liposome composite sustained-release microneedle and preparation method thereof
The invention belongs to the technical field of microneedle drug delivery systems, and particularly relates to a rapid separation type lipidosome composite sustained-release microneedle and a preparation method thereof.The microneedle comprises a needle tip layer, a separation layer and a base layer...
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| creator | HU JINGWEN HUANG PING YANG LI HOU AILIN YANG YAO LIN JIACHAN ZENG XIAOWEI |
| description | The invention belongs to the technical field of microneedle drug delivery systems, and particularly relates to a rapid separation type lipidosome composite sustained-release microneedle and a preparation method thereof.The microneedle comprises a needle tip layer, a separation layer and a base layer, the separation layer is located between the needle tip layer and the base layer, lipidosome is dispersed in the needle tip layer, and the separation layer is located between the needle tip layer and the base layer. The needle point layer and the lipidosome of the needle point layer can carry drugs, and the drugs can be different drugs; the needle tip layer is prepared from glucan and chitosan; the liposome is prepared from phosphatidylcholine and cholesterol; the separation layer is prepared from a high-molecular polymer with a polar group and small-molecular sugar; the base layer is prepared from a high-molecular polymer material. The separated liposome composite microneedle has the advantages of good biocompati |
| format | Patent |
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The needle point layer and the lipidosome of the needle point layer can carry drugs, and the drugs can be different drugs; the needle tip layer is prepared from glucan and chitosan; the liposome is prepared from phosphatidylcholine and cholesterol; the separation layer is prepared from a high-molecular polymer with a polar group and small-molecular sugar; the base layer is prepared from a high-molecular polymer material. 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The needle point layer and the lipidosome of the needle point layer can carry drugs, and the drugs can be different drugs; the needle tip layer is prepared from glucan and chitosan; the liposome is prepared from phosphatidylcholine and cholesterol; the separation layer is prepared from a high-molecular polymer with a polar group and small-molecular sugar; the base layer is prepared from a high-molecular polymer material. The separated liposome composite microneedle has the advantages of good biocompati</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | Rapid separation type liposome composite sustained-release microneedle and preparation method thereof |
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