Use of thiazolidinone in preparing medicine for treating and preventing neudrodegenerative disorders

Use of thiazolidinone in preparing medicine for treating and preventing neudrodegenerative disorders

用5-〔〔3，5-双(1，1-二甲基乙基)-4-羟基苯基〕亚甲基〕-2-亚氨基-4-噻唑烷酮或其药物可接受的盐治疗和预防神经变性疾病，如早老性痴呆、中风、多发性硬化和头部创伤。 PCT No. PCT/US97/11586 Sec. 371 Date Oct. 28, 1998 Sec. 102(e) Date Oct. 28, 1998 PCT Filed Jul. 1, 1997 PCT Pub. No. WO98/02160 PCT Pub. Date Jan. 22, 1998Neurodegenerative disorders, i.e., Alzheimer's dis...

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Bibliographische Detailangaben
Hauptverfasser: R.D. DYER, L.J. ROBICHAUD, R.T. CARROLL
Format: Patent
Sprache:chi ; eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:用5-〔〔3，5-双(1，1-二甲基乙基)-4-羟基苯基〕亚甲基〕-2-亚氨基-4-噻唑烷酮或其药物可接受的盐治疗和预防神经变性疾病，如早老性痴呆、中风、多发性硬化和头部创伤。 PCT No. PCT/US97/11586 Sec. 371 Date Oct. 28, 1998 Sec. 102(e) Date Oct. 28, 1998 PCT Filed Jul. 1, 1997 PCT Pub. No. WO98/02160 PCT Pub. Date Jan. 22, 1998Neurodegenerative disorders, i.e., Alzheimer's disease, stroke, multiple sclerosis and head trauma are treated with 5-[[{3,5-bis(1,1,-dimethylethyl)-4-hydroxyphenyl]methylene]-2-imino-4-thiazolidinone or a pharmaceutically acceptable salt thereof.