Voltage calibration device and method and imaging system

The embodiment of the invention discloses a voltage calibration device and method and an imaging system. The voltage calibration device comprises a channel selector and a calibration unit. Wherein the input end of the channel selector is selectively connected with to-be-calibrated channels of the plurality of detectors so as to receive the common-mode voltage of at least one to-be-calibrated channel. The first input end of the calibration unit is connected with the output end of the channel selector, the output end of the calibration unit is connected with a plurality of to-be-calibrated channels, and the calibration unit adjusts the common-mode voltage of the to-be-calibrated channels into calibration common-mode voltage, so that the to-be-calibrated channels are detected by using the calibration common-mode voltage. The common-mode voltages of the to-be-calibrated channels are adjusted to be within the same preset voltage range through the calibration unit, so that the channel calibration common-mode voltag